respiration disorders

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

---

Study Counts

Type	Study_count
Total_Studies	184
interventional	114
Observational	66
Registry	4

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Other	19
Device	18
Drug	13
Drug|placebo	13
Procedure	10
Behavioral	8
Biological|placebo	8
Diagnostic Test	6
Biological	2
Dietary Supplement	2
Behavioral|Biological|Other	1
Behavioral|Device|placebo	1
Behavioral|Other	1
Biological|Drug	1
Combination Product	1
Combination Product|placebo	1
Device|Drug	1
Device|Other	1
Device|Procedure	1
Diagnostic Test|Other	1
Dietary Supplement|Other	1
Drug|Other	1
Drug|placebo|Procedure	1
Drug|Procedure	1
Other|Procedure	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	20
NA	11
Belgium	7
France	7
Canada	6
United Kingdom	6
Australia	5
Switzerland	4
Denmark	3
Israel	3
Korea, Republic of	3
Mexico	3
Argentina	2
Austria	2
China	2
India	2
Portugal	2
Spain	2
Turkey	2
Australia|France	1
Belgium|United States|Canada|France|Germany|Italy|Spain|United Kingdom	1
Brazil	1
Canada|Germany|United Kingdom	1
Czech Republic|Poland|United Kingdom	1
Estonia|Finland|France|Italy|Spain	1
France|Italy|Spain|Tunisia	1
Hong Kong|Korea, Republic of|Philippines|Taiwan	1
Iran, Islamic Republic of	1
Ireland	1
Italy	1
Japan	1
Kyrgyzstan	1
Peru	1
Saint Kitts and Nevis	1
Singapore	1
Sweden|United Kingdom	1
United States|Argentina|Canada|Chile|Colombia|Italy|Malaysia|Mexico|Peru|Philippines|Romania|Russian Federation|Serbia|Spain|Taiwan|Thailand|Ukraine	1
United States|Belgium|France|Germany|Italy	1
United States|Puerto Rico	1
United States|Uganda	1
Vietnam	1

Sites per Study

Site_count	Study_Count
1	84
2	4
3	6
4	1
5	4
6	1
7	1
8	1
9	1
14	3
15	2
19	2
20	1
30	1
67	1
338	1

Phase

Phase	Study_Count
N/A	73
Phase 1	12
Phase 2	11
Phase 4	9
Phase 3	5
Phase 1/Phase 2	2
Early Phase 1	1
Phase 2/Phase 3	1

Number of Arms

Number_of_Arms	Count_of_Studies
1	20
2	65
3	8
4	11
5	1
6	2
7	1
10	1
11	1
NA	4

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	30	3.0000	9.00000	100	10.0000	54	64.0	32.00
1st Qu.	30	42.0000	28.50000	150	45.5000	54	132.0	44.00
Median	30	99.0000	53.50000	200	83.0000	54	436.0	223.00
Mean	30	219.6438	68.08333	200	168.7273	54	334.4	17394.56
3rd Qu.	30	160.0000	65.25000	250	172.5000	54	454.0	605.00
Max.	30	2728.0000	272.00000	300	606.0000	54	586.0	152723.00

Trial Group Type

group_type	Group_Count
Experimental	152
Active Comparator	43
Placebo Comparator	27
No Intervention	23
Other	14
Sham Comparator	4
NA	4

Intervention Model

intervention_model	Study_Count
Parallel Assignment	69
Single Group Assignment	29
Crossover Assignment	14
Sequential Assignment	1
NA	1

Primary Purpose

primary_purpose	Study_Count
Treatment	49
Prevention	19
Diagnostic	13
Supportive Care	11
Basic Science	8
Other	6
Health Services Research	4
Screening	2
Device Feasibility	1
NA	1

Observational Studies

Studies by Country

Country	Study_Count
United States	16
NA	8
France	6
United Kingdom	5
Belgium	3
Austria	2
Brazil	2
Canada	2
Germany	2
Israel	2
United States|Italy|Spain	2
Vietnam	2
Belgium|Vietnam	1
Botswana	1
China	1
Colombia	1
Denmark	1
Finland	1
Japan	1
Kazakhstan	1
Portugal	1
Spain	1
Sweden	1
Switzerland	1
Thailand	1
United States|Australia|Canada|Italy	1

Sites per Study

Site_count	Study_Count
1	54
2	3
3	4
5	2
6	1
13	1
24	1

Enrollment Metrics

Measure	Observational
Min	12.00
1st Qu	77.00
Median	240.00
Mean	10263.77
3rd Qu	1001.00
Max	180000.00

Observation Model

observational_model	Study_Count
Cohort	39
Other	8
Case-Control	7
Case-Only	5
Case Control	3
NA	2
Defined Population, Natural History	1
Family-Based	1

Time Perspective

time_perspective	Study_Count
Prospective	46
Cross-Sectional	11
Retrospective	6
Cross-Sectional, Prospective	1
Other	1
NA	1

Registries

Studies by Country

Country	Study_Count
Korea, Republic of	1
Norway	1
United Kingdom	1
United States	1

Sites per Study

Site_count	Study_Count
1	3
4	1

Enrollment Metrics

Measure	Registries
Min	350.0
1st Qu	1266.5
Median	5536.0
Mean	27855.5
3rd Qu	32125.0
Max	100000.0

Registry Model

observational_model	Study_Count
Cohort	3
Case-Control	1

Time Perspective

time_perspective	Study_Count
Prospective	2
Cross-Sectional	1
Other	1

Follow-up

target_duration	Study_Count
10 Years	1
20 Years	1
5 Years	1
6 Months	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04397692	Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (US Trial)	https://ClinicalTrials.gov/show/NCT04397692	Recruiting	Beyond Air Ltd	2020-09-30
NCT03799666	(Re)Vitalizing Pulmonary Rehabilitation for Patients With Chronic Respiratory Diseases	https://ClinicalTrials.gov/show/NCT03799666	Completed	Aveiro University	2019-12-30
NCT03372252	Impact of the Inspiratory Cortical Control on the Outcome of the Ventilatory Weaning Test in Patients Intubated in Resuscitation	https://ClinicalTrials.gov/show/NCT03372252	Recruiting	Poitiers University Hospital	2020-01-30
NCT03819023	Validation of RespiLife for Detection of Respiratory Suppression	https://ClinicalTrials.gov/show/NCT03819023	Completed	Bioresp Technologies, Inc.	2019-03-02
NCT03342495	Evaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial	https://ClinicalTrials.gov/show/NCT03342495	Recruiting	University of Calgary	2019-12-31
NCT03334916	A Clinical Trial to Evaluate the Efficacy and Safety of YMC026 in Respiratory Disease Patients	https://ClinicalTrials.gov/show/NCT03334916	Completed	Yuhan Corporation	2018-04-11
NCT03333850	Technology Assisted Physical Activity Among Hospitalised Patients With Respiratory Disease	https://ClinicalTrials.gov/show/NCT03333850	Completed	Frederiksberg University Hospital	2018-06-30
NCT03327610	Selecting the Best Ventilator Hyperinflation Settings	https://ClinicalTrials.gov/show/NCT03327610	Completed	Centro Universitário Augusto Motta	2017-08-31
NCT03326063	Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban	https://ClinicalTrials.gov/show/NCT03326063	Recruiting	Brigham and Women’s Hospital	2020-10-31
NCT03294057	Collaborative Care With Smart Health Management Program for Patients With Chronic Illness	https://ClinicalTrials.gov/show/NCT03294057	Active, not recruiting	Seoul National University Hospital	2018-06-07
NCT03266016	Real-time Effort Driven VENTilator Management	https://ClinicalTrials.gov/show/NCT03266016	Recruiting	Children’s Hospital Los Angeles	2022-06-01
NCT03238209	Surface Respiratory Electromyography Measurements During Treadmill Exercise in Stable Patients With COPD	https://ClinicalTrials.gov/show/NCT03238209	Completed	Guangzhou Institute of Respiratory Disease	2016-12-15
NCT03230968	Use of a Respiratory Care Model in Population Older Than 15 Years in Orizaba, Veracruz Mexico	https://ClinicalTrials.gov/show/NCT03230968	Completed	Instituto Nacional de Salud Publica, Mexico	2015-03-31
NCT03201211	A Long Term Follow-up Study up to 4 Years After Study Vaccination to Assess Immunogenicity and Safety of the Investigational Vaccine in Adults	https://ClinicalTrials.gov/show/NCT03201211	Completed	GlaxoSmithKline	2020-03-19
NCT03153800	Autologous Bronchial Basal Cells Transplantation for Treatment of CRD Including COPD, BE and PF	https://ClinicalTrials.gov/show/NCT03153800	Recruiting	Regend Therapeutics	2021-04-04
NCT03151395	Occurrence of Potential Bacterial and Viral Pathogens in Stable Chronic Obstructive Pulmonary Disease and During Acute Exacerbations of the Disease, in Asia Pacific	https://ClinicalTrials.gov/show/NCT03151395	Completed	GlaxoSmithKline	2020-04-06
NCT03119727	Clinical Evaluation of FreeO2 (Version 4) in All Patients Receiving Oxygen	https://ClinicalTrials.gov/show/NCT03119727	Recruiting	Laval University	2019-06-30
NCT03089515	Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust	https://ClinicalTrials.gov/show/NCT03089515	Recruiting	NYU Langone Health	2020-09-07
NCT03028350	Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD)	https://ClinicalTrials.gov/show/NCT03028350	Recruiting	Cumberland Pharmaceuticals	2021-04-30
NCT02955108	The Effect of Distractive Auditory Stimuli (Music) on Dyspnea and Anxiety During Exercise in Adults With Chronic Respiratory Diseases	https://ClinicalTrials.gov/show/NCT02955108	Enrolling by invitation	NYU Langone Health	2020-03-31
NCT02943551	Dialogue Around Respiratory Illness Treatment	https://ClinicalTrials.gov/show/NCT02943551	Active, not recruiting	Seattle Children’s Hospital	2020-05-30
NCT02924818	Cohort for Research and Innovation in Chronic Inflammatory Respiratory Diseases	https://ClinicalTrials.gov/show/NCT02924818	Recruiting	CHU de Reims	2021-11-30
NCT02898129	Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City	https://ClinicalTrials.gov/show/NCT02898129	Completed	Brugmann University Hospital	2017-07-31
NCT02881814	UltraSound for Accurate Decisions in Chest PhysioTherapy	https://ClinicalTrials.gov/show/NCT02881814	Recruiting	Groupe Hospitalier Paris Saint Joseph	2020-05-31
NCT02817035	Study of Neural Inspiratory Time and Expiratory Delay in Patient and Health During Spontaneous Breathing and Ventilation	https://ClinicalTrials.gov/show/NCT02817035	Completed	The First Affiliated Hospital of Guangzhou Medical University	2016-11-30
NCT02813954	The Predictive Value of Amniotic Fluid pH and Electrolytes on Neonatal Respiratory Disorders	https://ClinicalTrials.gov/show/NCT02813954	Completed	Kanuni Sultan Suleyman Training and Research Hospital	2016-04-30
NCT02723890	The Efficacy and Safety of Using the Novel Tyto Device	https://ClinicalTrials.gov/show/NCT02723890	Completed	Rabin Medical Center	2017-01-31
NCT02717650	The Alfred Step Test Exercise Protocol Developed for Adults With Cystic Fibrosis: The A-STEP and A-STEPmax Study’s.	https://ClinicalTrials.gov/show/NCT02717650	Recruiting	The Alfred	2020-08-31
NCT02715219	The Effect of an AEP on Patient’s Knowledge Regarding Asthma Disease and Inhaler Technique: RCT	https://ClinicalTrials.gov/show/NCT02715219	Completed	Clinical Research Centre, Malaysia	2016-09-30
NCT02698007	Safety and Benefits of Using Laryngeal Mask Airway to Keep Airway Potency During Fiber-optic Bronchoscopy	https://ClinicalTrials.gov/show/NCT02698007	Completed	Rabin Medical Center	2016-10-31
NCT02658422	Bioequivalence of GW483100 10 Milligram (mg) Tablets in Healthy Subjects Under Fasting Conditions	https://ClinicalTrials.gov/show/NCT02658422	Completed	GlaxoSmithKline	2015-09-21
NCT03392129	Ai Chi Method for Children With Asthma	https://ClinicalTrials.gov/show/NCT03392129	Recruiting	Universidade Federal do Rio Grande do Norte	2020-07-20
NCT02547974	A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the Investigational GSK Biologicals’ GSK3277511A Vaccine in Adults.	https://ClinicalTrials.gov/show/NCT02547974	Completed	GlaxoSmithKline	2017-03-31
NCT02471872	Behavioral Research of Environment and Air Pollution Through Education	https://ClinicalTrials.gov/show/NCT02471872	Active, not recruiting	University of California, San Francisco	2020-12-31
NCT02322671	Relative Bioavailability Study of Two Montelukast Sodium (GW483100) 5 Milligrams (mg) Chewable Tablets and One Reference Montelukast Sodium 5 mg Chewable Tablet in Healthy Adult Subjects	https://ClinicalTrials.gov/show/NCT02322671	Completed	GlaxoSmithKline	2015-04-20
NCT02316379	Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration	https://ClinicalTrials.gov/show/NCT02316379	Recruiting	Children’s Hospital Medical Center, Cincinnati	2020-10-31
NCT02272049	Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults	https://ClinicalTrials.gov/show/NCT02272049	Recruiting	Children’s Hospital Medical Center, Cincinnati	2020-10-31
NCT02240069	Wood Smoke Interventions in Native American Populations	https://ClinicalTrials.gov/show/NCT02240069	Active, not recruiting	University of Montana	2020-06-30
NCT02216357	Trial to Determine the Safety of Oral Ifetroban in Patients With a History of Aspirin Exacerbated Respiratory Disease	https://ClinicalTrials.gov/show/NCT02216357	Completed	Cumberland Pharmaceuticals	2016-01-31
NCT02102009	Nutritional Supplementation in Adults With Chronic Respiratory Disease	https://ClinicalTrials.gov/show/NCT02102009	Completed	Laboratorios Ordesa	2015-05-31
NCT02084043	In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation	https://ClinicalTrials.gov/show/NCT02084043	Completed	University Hospital St Luc, Brussels	2015-06-30
NCT02079701	Effectiveness of the Pneumococcal Polysaccharide Vaccine in Military Recruits	https://ClinicalTrials.gov/show/NCT02079701	Completed	Naval Health Research Center	2003-06-30
NCT02075541	A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GlaxoSmithkline (GSK) Biologicals’ Investigational Vaccine GSK2838504A When Administered to Chronic Obstructive Pulmonary Disease (COPD) Patients With Persistent Airflow Obstruction.	https://ClinicalTrials.gov/show/NCT02075541	Completed	GlaxoSmithKline	2017-04-19
NCT02064738	High Omega-3/Low Omega-6 Treatment Diet for Aspirin-exacerbated Respiratory Disease (AERD)	https://ClinicalTrials.gov/show/NCT02064738	Completed	Brigham and Women’s Hospital	2017-03-31
NCT01283009	Extended Steroid in CAP(e)	https://ClinicalTrials.gov/show/NCT01283009	Completed	VA Office of Research and Development	2016-07-31
NCT03351504	Solar Lighting to Reduce Indoor Air Pollution in Rural Uganda	https://ClinicalTrials.gov/show/NCT03351504	Active, not recruiting	Massachusetts General Hospital	2019-10-31
NCT01867281	The Effect of Aspirin Desensitization on Patients With Aspirin-exacerbated Respiratory Diseases	https://ClinicalTrials.gov/show/NCT01867281	Completed	Tehran University of Medical Sciences	2014-06-30
NCT01818024	A Study to Investigate the Safety Tolerability Pharmacokinetics, and Pharmacodynamics of Inhaled and Intravenous GSK2862277 in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT01818024	Completed	GlaxoSmithKline	2013-10-25
NCT01778465	Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease	https://ClinicalTrials.gov/show/NCT01778465	Completed	Lawson Health Research Institute	2014-03-31
NCT01774201	Respiratory Function and Walking Capacity in Multiple Sclerosis	https://ClinicalTrials.gov/show/NCT01774201	Completed	Region Örebro County	2014-12-31
NCT01678677	A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GSK Biologicals’ Non-typeable Haemophilus Influenzae (NTHi) Investigational Vaccine (GSK2838497A) in Current and Former Smokers	https://ClinicalTrials.gov/show/NCT01678677	Completed	GlaxoSmithKline	2014-01-30
NCT01657526	Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline (GSK) Biologicals’ Non-typeable Haemophilus Influenzae (NTHI) Vaccine	https://ClinicalTrials.gov/show/NCT01657526	Completed	GlaxoSmithKline	2013-11-25
NCT00835003	Timing of Planned Caesarean Section and Morbidity of the Newborn	https://ClinicalTrials.gov/show/NCT00835003	Completed	Aarhus University Hospital	2011-11-30
NCT01597375	Therapeutic Control of Aspirin-Exacerbated Respiratory Disease (Aspirin)	https://ClinicalTrials.gov/show/NCT01597375	Completed	Brigham and Women’s Hospital	2016-12-14
NCT01587807	A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Inhaled GSK1995057	https://ClinicalTrials.gov/show/NCT01587807	Completed	GlaxoSmithKline	2012-11-19
NCT01533220	Efficacy of Nasal Naphazoline Hydrocloride + Pheniramine Maleate + Panthenol Compared With Naphazoline Hydrocloride in the Symptomatic Control of Nasal Congestion and Nasopharyngeal	https://ClinicalTrials.gov/show/NCT01533220	Completed	EMS	2013-08-31
NCT01532180	Safety and Efficacy of a Hypoglossal Nerve Implant for the Treatment of Obstructive Sleep Apnea (OSA)	https://ClinicalTrials.gov/show/NCT01532180	Completed	LivaNova	2011-12-31
NCT01516437	A Study to Assess Immunity to Specific Microbial Antigens in Healthy Smokers and Non-smokers and in Subjects With Stable COPD	https://ClinicalTrials.gov/show/NCT01516437	Completed	GlaxoSmithKline	2012-06-28
NCT01505582	Inspiratory Muscle Training and Low Back Pain	https://ClinicalTrials.gov/show/NCT01505582	Completed	KU Leuven	2013-12-31
NCT01476046	Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects.	https://ClinicalTrials.gov/show/NCT01476046	Completed	GlaxoSmithKline	2012-06-17
NCT01443845	Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)	https://ClinicalTrials.gov/show/NCT01443845	Completed	AstraZeneca	2015-11-30
NCT01390753	Role of Human Milk Bank in the Protection of Severe Respiratory Disease in Very Low Birth Weight Premature Infants	https://ClinicalTrials.gov/show/NCT01390753	Completed	Fundacion Infant	2016-12-31
NCT01360398	Infectious Pathogens in Acute Respiratory Illness in Adults and Elderly	https://ClinicalTrials.gov/show/NCT01360398	Completed	GlaxoSmithKline	2014-06-27
NCT01347411	Effectiveness of the Treatment With Continuous Positive Airway Pressure(CPAP)in Stable Heart Failure With Ejection Fraction More Than 45% and Sleep Disordered Breathing	https://ClinicalTrials.gov/show/NCT01347411	Completed	Basque Health Service	2011-04-30
NCT04442256	Effect of Dupilumab on Aspirin Intolerance	https://ClinicalTrials.gov/show/NCT04442256	Recruiting	Medical University of Vienna	2022-12-31
NCT04394117	Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY Disease	https://ClinicalTrials.gov/show/NCT04394117	Recruiting	The George Institute	2021-01-30
NCT04386408	Evaluation of the Effect of a Combination of Plant Extracts (BSL_EP027) on the Incidence of Respiratory Infections	https://ClinicalTrials.gov/show/NCT04386408	Completed	Biosearch S.A.	2020-01-31
NCT04382768	Inhaled Ibuprofen to Treat COVID-19	https://ClinicalTrials.gov/show/NCT04382768	Recruiting	Química Luar SRL	2021-01-31
NCT04375293	Characterisation of the Nasal Microbiome in Patients With N-ERD	https://ClinicalTrials.gov/show/NCT04375293	Recruiting	Medical University of Vienna	2021-06-30
NCT04373070	Quality-of-Life Management for COPD Patients	https://ClinicalTrials.gov/show/NCT04373070	Recruiting	University of Zurich	2022-03-31
NCT04331054	Protective Role of Inhaled Steroids for Covid-19 Infection	https://ClinicalTrials.gov/show/NCT04331054	Recruiting	Assistance Publique - Hôpitaux de Paris	2020-07-13
NCT04322136	AMPLE-3: IPC Plus Talc vs VATS in Management of Malignant Pleural Effusion	https://ClinicalTrials.gov/show/NCT04322136	Recruiting	The University of Western Australia	2021-08-01
NCT04282369	Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room	https://ClinicalTrials.gov/show/NCT04282369	Recruiting	Kanuni Sultan Suleyman Training and Research Hospital	2020-08-01
NCT04266951	Singstrong: Singing for Better Lung Health	https://ClinicalTrials.gov/show/NCT04266951	Active, not recruiting	University of Limerick	2020-03-31
NCT04086953	Validation of a Walk-Time Limit Test (WTLT) Derived From the 6-Minute Walk Test (6-MWT) in Patients With Chronic Cardiovascular or Respiratory Diseases	https://ClinicalTrials.gov/show/NCT04086953	Recruiting	University Hospital, Brest	2022-01-31
NCT04017780	Asynchronies in Pediatric Noninvasive Ventilation	https://ClinicalTrials.gov/show/NCT04017780	Recruiting	Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico	2021-07-15
NCT03976167	Comparison of Oxygen Adminstration by Nasal Cannula and High Flow Cannula During Bronchoscopy	https://ClinicalTrials.gov/show/NCT03976167	Completed	Hospital Son Espases	2019-02-28
NCT03973749	Effects of a High or Low Salycilate Diet on Urinary LTE4 and Clinical Features in AERD	https://ClinicalTrials.gov/show/NCT03973749	Active, not recruiting	Instituto Nacional de Enfermedades Respiratorias	2019-05-31
NCT03930511	Telemonitoring Physical Activity in Daily Life on Chronic Respiratory Patients	https://ClinicalTrials.gov/show/NCT03930511	Active, not recruiting	University of Lisbon	2018-10-31
NCT03894969	Study to Assess the Immunogenicity and Safety of GSK’s Investigational Vaccine (GSK3277511A) When Given to Healthy Smokers and Ex-smokers After Administration of Shingrix Vaccine	https://ClinicalTrials.gov/show/NCT03894969	Active, not recruiting	GlaxoSmithKline	2020-08-14
NCT03776773	Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study	https://ClinicalTrials.gov/show/NCT03776773	Completed	University Hospital, Grenoble	2020-01-25
NCT03750110	Yorkshire Enhanced Stop Smoking Study	https://ClinicalTrials.gov/show/NCT03750110	Recruiting	University of Nottingham	2021-02-28
NCT03732222	Stretching of the Diaphragm and Cervical Impulse Technique and Its Possible Spirometric Changes	https://ClinicalTrials.gov/show/NCT03732222	Completed	Cardenal Herrera University	2018-11-06
NCT03670914	Diagnosis of Sleep-Related Respiratory Disorders in Patients With Narcotic Medications	https://ClinicalTrials.gov/show/NCT03670914	Recruiting	Kaiser Permanente	2023-01-31
NCT03656198	Non-specific Effects of Rabies Vaccine	https://ClinicalTrials.gov/show/NCT03656198	Enrolling by invitation	Ross University School of Veterinary Medicine	2020-07-31
NCT03654092	Home-based Exercise Training for COPD Patients (HOMEX-2)	https://ClinicalTrials.gov/show/NCT03654092	Recruiting	University of Zurich	2020-10-31
NCT03643757	Epidural Analgesia and Postoperative Respiratory Functions (EPAPRES)	https://ClinicalTrials.gov/show/NCT03643757	Completed	Yedikule Training and Research Hospital	2017-08-01
NCT03632421	The ESTxENDS Trial-effects of Using Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig) on Respiratory Symptoms	https://ClinicalTrials.gov/show/NCT03632421	Recruiting	University of Bern	2023-06-30
NCT03627481	Sleep Quality After Nasosinusal Surgery in AERD Patients	https://ClinicalTrials.gov/show/NCT03627481	Enrolling by invitation	Instituto Nacional de Enfermedades Respiratorias	2019-12-31
NCT03595488	Dupilumab for Aspirin-exacerbated Respiratory Disease	https://ClinicalTrials.gov/show/NCT03595488	Active, not recruiting	Rochester General Hospital	2019-12-31
NCT03540901	Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude	https://ClinicalTrials.gov/show/NCT03540901	Active, not recruiting	University of Zurich	2020-12-31
NCT03461887	Home-based Exercise Training for COPD Patients	https://ClinicalTrials.gov/show/NCT03461887	Recruiting	University of Zurich	2019-12-31
NCT03432117	Evaluate Efficacy of Respiratory Rehabilitation Personalized Mobile Services for Respiratory Diseases	https://ClinicalTrials.gov/show/NCT03432117	Completed	Asan Medical Center	2017-12-28
NCT03420209	The Effect of Proprioceptive Neuromuscular Facilitation (PNF) Technique for Children With Chronic Pulmonary Diseases.	https://ClinicalTrials.gov/show/NCT03420209	Active, not recruiting	Istanbul University	2020-11-01
NCT01255592	Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis	https://ClinicalTrials.gov/show/NCT01255592	Completed	AstraZeneca	2012-02-29
NCT01196533	A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters	https://ClinicalTrials.gov/show/NCT01196533	Completed	Cnoga Medical Ltd.	2013-07-31
NCT01113255	Validation of a Simulated Clinical Evaluation of Ventilators	https://ClinicalTrials.gov/show/NCT01113255	Completed	Assistance Publique - Hôpitaux de Paris	2011-09-30
NCT00988000	Initial Specialist Telephone Consultation With New Patients in Secondary Care	https://ClinicalTrials.gov/show/NCT00988000	Completed	Imperial College London	2010-04-30
NCT00864084	Does Pulmonary Rehabilitation Improve Balance in People With Respiratory Disease?	https://ClinicalTrials.gov/show/NCT00864084	Completed	University of Manitoba	2009-06-30
NCT03650478	Assessment of NeuroBOX and NeuroPAP in Infants.	https://ClinicalTrials.gov/show/NCT03650478	Recruiting	St. Justine’s Hospital	2020-12-01
NCT00823056	The Effect of Probiotics on Infections in Toddlers	https://ClinicalTrials.gov/show/NCT00823056	Completed	Zealand University Hospital	2011-12-31
NCT04139356	The Effect of Spontaneous Respiration on Pulse-oximetry Measurements	https://ClinicalTrials.gov/show/NCT04139356	Recruiting	Universidad Autonoma de Nuevo Leon	2019-11-15
NCT01952431	Measurement and Evaluation of Total Lung Capacity (TLC) in the Field of Pulmonary Functional Testing (PFT)	https://ClinicalTrials.gov/show/NCT01952431	Completed	PulmOne Advanced Medical Devices, Ltd.	2013-09-30
NCT01796925	Targeted Hypoglossal Neurostimulation Study #2	https://ClinicalTrials.gov/show/NCT01796925	Completed	LivaNova	2013-09-30
NCT03443427	A Study to Test if a Third Dose of the Vaccine is Safe in Current and Former Smokers Aged 40 to 80 Years Old and to Gather Information on the Immune Response Following the Third Dose of the Vaccine	https://ClinicalTrials.gov/show/NCT03443427	Active, not recruiting	GlaxoSmithKline	2019-12-31
NCT03281876	A Study to Test if the Vaccine is Working Well in Chronic Obstructive Pulmonary Disease (COPD) Patients Aged 40 to 80 Years Old to Reduce Episodes of Worsening Symptoms and to Gather Further Information on Safety and Immune Response.	https://ClinicalTrials.gov/show/NCT03281876	Completed	GlaxoSmithKline	2020-03-26
NCT02950805	A Study to Assess the Effect of AZD5634 on Mucociliary Clearance, Safety, Tolerability and Pharmacokinetic Parameters in Patients With Cystic Fibrosis	https://ClinicalTrials.gov/show/NCT02950805	Completed	AstraZeneca	2018-04-12
NCT04147013	Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients With CRS	https://ClinicalTrials.gov/show/NCT04147013	Recruiting	Lawson Health Research Institute	2020-12-31
NCT03632577	High Flow Oxygen VERSUS Non Invasive Ventilation Associated to Automated Flow Oxygen Titration After Patient Extubation	https://ClinicalTrials.gov/show/NCT03632577	Recruiting	University Hospital, Toulouse	2019-12-19
NCT00719784	Vibration Response Imaging in the Diagnosis of Pulmonary Disease	https://ClinicalTrials.gov/show/NCT00719784	Completed	Singapore General Hospital	2009-06-30
NCT00455767	Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients	https://ClinicalTrials.gov/show/NCT00455767	Completed	Debiopharm International SA	2007-09-30
NCT00360464	A Trial Of Azithromycin SR For The Treatment Of Acute Bronchitis And Secondary Infection Of Chronic Respiratory Diseases	https://ClinicalTrials.gov/show/NCT00360464	Completed	Pfizer	2007-06-30
NCT00202319	Effectiveness of Sedation Management in an Australian Intensive Care Unit	https://ClinicalTrials.gov/show/NCT00202319	Completed	Melbourne Health	NA
NCT00004424	Randomized Study of Propofol Versus Fentanyl and Midazolam in Pediatric Patients Requiring Mechanical Ventilation and Sedation Therapy	https://ClinicalTrials.gov/show/NCT00004424	Completed	FDA Office of Orphan Products Development	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03392363	Diagnosing Respiratory Disease in Children Using Cough Sounds 2	https://ClinicalTrials.gov/show/NCT03392363	Completed	ResApp Health Limited	2018-10-19
NCT03383601	Сohort Study to Evaluate Exacerbations, Respiratory Symptoms, Physical Exercise Intolerance and Lung Functions Among Participants Who Use IQOS With Heatsticks Compared to Smokers of Conventional Cigarettes	https://ClinicalTrials.gov/show/NCT03383601	Active, not recruiting	Kazakhstan Academy of Preventive Medicine	2023-06-30
NCT03322254	How Respiratory Pathogens Panel Results Affect Patients’ Plan of Care	https://ClinicalTrials.gov/show/NCT03322254	Enrolling by invitation	Data Collection Analysis Business Management	2020-10-24
NCT03319446	Collection of Anonymized Samples	https://ClinicalTrials.gov/show/NCT03319446	Enrolling by invitation	BioFire Diagnostics, LLC	2027-10-31
NCT03264417	Pulmonary Function Test Study - Automated Interpretation	https://ClinicalTrials.gov/show/NCT03264417	Completed	KU Leuven	2017-12-30
NCT03224286	Pressure Sensitive Mats for Patient Monitoring in the NICU	https://ClinicalTrials.gov/show/NCT03224286	Recruiting	Children’s Hospital of Eastern Ontario	2019-12-31
NCT02877121	Respiratory Muscle Function and Neural Respiratory Drive in Interstitial Lung Disease	https://ClinicalTrials.gov/show/NCT02877121	Completed	The First Affiliated Hospital of Guangzhou Medical University	2016-09-30
NCT02754947	Need for the Assessment and Consultation Team (ACT) Following Anesthetic Care	https://ClinicalTrials.gov/show/NCT02754947	Completed	Nationwide Children’s Hospital	2016-02-29
NCT02681848	What Are the Effects of Varenicline Compared With Nicotine Replacement Therapy on Long Term Smoking Cessation and Clinically Important Outcomes?	https://ClinicalTrials.gov/show/NCT02681848	Active, not recruiting	University of Bristol	2014-03-31
NCT02546479	Follow-Up Study of People Treated for Scoliosis	https://ClinicalTrials.gov/show/NCT02546479	Completed	National Institutes of Health Clinical Center (CC)	2016-08-16
NCT02517983	Phenotyping the Chronic Respiratory Diseases (CRD) in Ho Chi Minh City, Vietnam	https://ClinicalTrials.gov/show/NCT02517983	Completed	Brugmann University Hospital	2016-09-30
NCT02406053	Oxidative Damage and Antioxidant Mechanisms in COPD	https://ClinicalTrials.gov/show/NCT02406053	Completed	Yuzuncu Yıl University	2014-07-31
NCT02261337	Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease?	https://ClinicalTrials.gov/show/NCT02261337	Active, not recruiting	Royal Brompton & Harefield NHS Foundation Trust	2018-07-31
NCT02229994	Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases	https://ClinicalTrials.gov/show/NCT02229994	Completed	Assistance Publique - Hôpitaux de Paris	2014-03-27
NCT01734629	Pulmonary Disease in Patients Referred for Coronary CT	https://ClinicalTrials.gov/show/NCT01734629	Completed	University of Sao Paulo General Hospital	2013-12-31
NCT01727518	The Austrian LEAD (Lung hEart sociAl boDy) Study	https://ClinicalTrials.gov/show/NCT01727518	Enrolling by invitation	LudwLudwig Boltzmann Institute for COPD and Respiratory Epidemiology	2016-05-31
NCT01690533	Special Drug Use Investigation - Assessment of Efficacy and Safety in Treating Secondary Infection of Chronic Respiratory Disease	https://ClinicalTrials.gov/show/NCT01690533	Completed	Bayer	2010-12-14
NCT01631773	A Comparison of microRNA Samples in Patients With Nasal Polyps and Aspirin Exacerbated Respiratory Disease and Those With Nasal Polyps Only	https://ClinicalTrials.gov/show/NCT01631773	Completed	University of South Florida	2012-06-30
NCT01607216	Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies	https://ClinicalTrials.gov/show/NCT01607216	Completed	University of Rochester	2015-07-31
NCT01565954	Sleep Respiratory Disorders Evaluation in Sickle Cell Disease Children	https://ClinicalTrials.gov/show/NCT01565954	Completed	Assistance Publique - Hôpitaux de Paris	2018-08-31
NCT01435187	Prematurity and Respiratory Outcomes Program (PROP)	https://ClinicalTrials.gov/show/NCT01435187	Completed	University of Pennsylvania	2015-04-30
NCT01395862	Special Drug Use Investigation for ADOAIR (Fluticasone/Salmeterol)	https://ClinicalTrials.gov/show/NCT01395862	Completed	GlaxoSmithKline	2012-09-30
NCT01395849	Drug Use Investigation for ADOAIR (Fluticasone/Salmeterol)	https://ClinicalTrials.gov/show/NCT01395849	Completed	GlaxoSmithKline	2009-09-30
NCT01320072	Diagnosis of Aspirin Hypersensitivity in Aspirin Exacerbated Respiratory Disease	https://ClinicalTrials.gov/show/NCT01320072	Enrolling by invitation	Montefiore Medical Center	2016-10-31
NCT04413292	Survivin and Fibulin-3 in Benign and Malignant Respiratory Diseases	https://ClinicalTrials.gov/show/NCT04413292	Completed	South Valley University	2019-12-30
NCT04388579	Screening Patients for a Strategic Shift to Pulmonary Telerehabilitation Because of COVID-19	https://ClinicalTrials.gov/show/NCT04388579	Completed	University of Lisbon	2020-03-27
NCT04361669	Hospice Quality Score Assessment Post Pharmacist Intervention	https://ClinicalTrials.gov/show/NCT04361669	Active, not recruiting	Tabula Rasa HealthCare	2023-04-30
NCT04284891	Critical Respiratory Diseases in Ex-preterm Infants in PICU	https://ClinicalTrials.gov/show/NCT04284891	Recruiting	National Children’s Hospital, Vietnam	2020-11-30
NCT04262271	A Study to Identify Errors in Inhaler Technique in Adults	https://ClinicalTrials.gov/show/NCT04262271	Recruiting	Portsmouth Hospitals NHS Trust	2021-02-28
NCT04232579	Development of Predictive Biomarkers for the Diagnosis and Treatment of Asthma and COPD in Vietnam.	https://ClinicalTrials.gov/show/NCT04232579	Recruiting	Brugmann University Hospital	2021-01-31
NCT04140825	Within-Breath Total Respiratory Input Impedance in Healthy Adult Subjects	https://ClinicalTrials.gov/show/NCT04140825	Recruiting	Restech Srl	2020-12-31
NCT04125888	Impact of AIT on Allergic Rhinitis and Asthma	https://ClinicalTrials.gov/show/NCT04125888	Active, not recruiting	ALK-Abelló A/S	2020-12-31
NCT04037839	Nasal High Flow Therapy in the Paediatric Home Setting	https://ClinicalTrials.gov/show/NCT04037839	Recruiting	Rabin Medical Center	2020-03-31
NCT04012216	Sleep Respiratory Disorders in Patients With Moderate to Severe Persistent Rhinitis	https://ClinicalTrials.gov/show/NCT04012216	Recruiting	University Hospital, Montpellier	2021-01-31
NCT04006964	Diagnostic Accuracy Of Forced Oscillation Technique To Detect Lung Function Anomalies	https://ClinicalTrials.gov/show/NCT04006964	Recruiting	Restech Srl	2019-12-31
NCT03934957	Hamburg City Health Study - a German Cohort Study	https://ClinicalTrials.gov/show/NCT03934957	Recruiting	Universitätsklinikum Hamburg-Eppendorf	2022-12-31
NCT03931226	Impact of Spa Treatments on the Consumption of Care in Children	https://ClinicalTrials.gov/show/NCT03931226	Active, not recruiting	University Hospital, Toulouse	2020-06-30
NCT03893227	Prevalence of Nasal Hyperreactivity in Chronic Upper Airway Inflammation	https://ClinicalTrials.gov/show/NCT03893227	Recruiting	Universitaire Ziekenhuizen Leuven	2020-06-30
NCT03849625	Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand	https://ClinicalTrials.gov/show/NCT03849625	Recruiting	Chulalongkorn University	2020-06-30
NCT03848156	Characterisation of Nasal Polyps in Patients With and Without Aspirin-exacerbated Respiratory Disease	https://ClinicalTrials.gov/show/NCT03848156	Completed	Medical University of Vienna	2019-11-30
NCT03797183	Genesis Electrical Impedance Tomography (EIT): A Preliminary Study	https://ClinicalTrials.gov/show/NCT03797183	Recruiting	University of Colorado, Denver	2022-02-28
NCT03785847	Normal Variability of Tidal Breathing Flow-volume Curves During Sleep in Healthy Children	https://ClinicalTrials.gov/show/NCT03785847	Completed	Tampere University Hospital	2019-09-17
NCT03744169	Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.	https://ClinicalTrials.gov/show/NCT03744169	Completed	University of Wisconsin, Madison	2020-02-29
NCT03741582	Urban Transformations and Health: The Case of TransMiCable in Bogotá	https://ClinicalTrials.gov/show/NCT03741582	Active, not recruiting	University of Los Andes, Columbia	2019-02-28
NCT03728595	Validation of a Predictive Score for HAST	https://ClinicalTrials.gov/show/NCT03728595	Recruiting	The Leeds Teaching Hospitals NHS Trust	2021-07-31
NCT03709199	Long Term Follow up of Children Enrolled in the REDvent Study	https://ClinicalTrials.gov/show/NCT03709199	Recruiting	Children’s Hospital Los Angeles	2023-01-01
NCT03704935	Long Term Effects and of a Pulmonary Rehabilitation Maintenance Program	https://ClinicalTrials.gov/show/NCT03704935	Completed	University Hospital, Montpellier	2019-04-30
NCT03661801	Novel Pleural Fluid, Biopsy and Serum Biomarkers for the Investigation of Pleural Effusions	https://ClinicalTrials.gov/show/NCT03661801	Recruiting	University of Oxford	2021-09-25
NCT03659838	Luftibus in the School: a Study on the Respiratory Health of Schoolchildren.	https://ClinicalTrials.gov/show/NCT03659838	Completed	University Children’s Hospital, Zurich	2016-12-15
NCT03598803	The Prevalence of Urinary Incontinence in Women and Men With Respiratory Diseases: a Questionnaire Survey	https://ClinicalTrials.gov/show/NCT03598803	Recruiting	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	2019-12-31
NCT03530059	Fast-Track Rehabilitation	https://ClinicalTrials.gov/show/NCT03530059	Completed	University Hospital, Grenoble	2019-06-21
NCT03499938	Structured Light Plethysmography in Obstructive Airways Disease	https://ClinicalTrials.gov/show/NCT03499938	Completed	Guy’s and St Thomas’ NHS Foundation Trust	2018-12-11
NCT03476473	Early Detection of Respiratory Disorders in Psychosis	https://ClinicalTrials.gov/show/NCT03476473	Enrolling by invitation	Fundación Marques de Valdecilla	2018-03-26
NCT03426488	Northern Sweden Health and Disease Study	https://ClinicalTrials.gov/show/NCT03426488	Recruiting	Umeå University	2026-01-31
NCT01156701	Prophylactic Efficacy of Relenza Against Influenza A and B	https://ClinicalTrials.gov/show/NCT01156701	Completed	GlaxoSmithKline	2010-05-31
NCT00840723	Bronchoscopy Assisted Sampling of Cells and Fluid From the Lower Respiratory Tract of Human Subjects	https://ClinicalTrials.gov/show/NCT00840723	Completed	University of North Carolina, Chapel Hill	2013-08-31
NCT02525354	Dietary Arachidonic Acid, Obesity and Atopic Respiratory Disease	https://ClinicalTrials.gov/show/NCT02525354	Completed	University of New Hampshire	2003-05-31
NCT04448470	Daytime Sleepiness in Patients With the Assessment of a Sleep-related Respiratory Disorder	https://ClinicalTrials.gov/show/NCT04448470	Recruiting	Heinrich-Heine University, Duesseldorf	2021-06-30
NCT00810186	Continuous Monitoring of Lung Ventilation	https://ClinicalTrials.gov/show/NCT00810186	Completed	Pneumedicare Ltd.	2015-08-31
NCT03290222	TRACK: Validation of the Portuguese Version	https://ClinicalTrials.gov/show/NCT03290222	Completed	Federal University of São Paulo	2018-02-01
NCT02973282	Diagnosing Respiratory Disease in Children Using Cough Sounds	https://ClinicalTrials.gov/show/NCT02973282	Completed	ResApp Health Limited	2017-12-31
NCT00750074	Slope of the Pressure-Time Waveform Predicts Resistance and Compliance in Mechanically Ventilated Subjects	https://ClinicalTrials.gov/show/NCT00750074	Completed	University of Iowa	2009-09-30
NCT00665405	Atelectasis During Delivery - Comparing Cesarian (c) -Section and Labor	https://ClinicalTrials.gov/show/NCT00665405	Completed	University of Sao Paulo	NA
NCT00532896	Impact of Weight Loss Following Bariatric Surgery on Pulmonary Function in Patients With Morbid Obesity	https://ClinicalTrials.gov/show/NCT00532896	Completed	Laval University	2011-01-31
NCT00197691	Botswana Pediatric Respiratory Disease and Bloodstream Infection Study	https://ClinicalTrials.gov/show/NCT00197691	Completed	Harvard School of Public Health	2005-10-31
NCT00192439	Study to Evaluate the Human Infection of the Lower Respiratory Tract in Children at High Risk	https://ClinicalTrials.gov/show/NCT00192439	Completed	MedImmune LLC	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03120481	Controls for Respiratory Diseases	https://ClinicalTrials.gov/show/NCT03120481	Recruiting	Seoul National University Hospital	2037-02-28
NCT04335773	COVID-19 in Hospitalised Norwegian Children - Risk Factors, Outcomes and Immunology	https://ClinicalTrials.gov/show/NCT04335773	Recruiting	University Hospital, Akershus	2030-12-31
NCT04263727	A Study of Patients With Chronic Disease	https://ClinicalTrials.gov/show/NCT04263727	Recruiting	Target PharmaSolutions, Inc.	2035-02-28
NCT04256720	The Multi-Ethnic Lifestyle Study	https://ClinicalTrials.gov/show/NCT04256720	Recruiting	University of Leicester	2023-11-01